Taking the main representative cities in China as the research object, this study analyzed the characteristics and topological characteristics of high-speed railway network, and identifies node cities and their functions in high-speed railway network. The Space-P method was used to build a high-speed network model, and the complex network theory and Pajek analysis software were used to analyze the topological structure and node centrality of of China′s high-speed rail network from the aspects of degree values, average path length, aggregation coefficient and node city centrality. The results showed that China′s high-speed rail network highly aggregated and connected as a whole, the eastern, central and coastal cities showed high aggregation, while the western cities had low high-speed rail network connectivity and weak aggregation. High-speed rail network had the characteristics of a small world, any two nodes could be connected by a small number of transit times, and a few cities need three transit times to be connected. In the high-speed rail network, the cities with large degree values were mainly concentrated in the east, central and coastal regions of China, while the cities in the west and northeast regions had less degree values and large degree centrality, and their proximity centrality was also large. Cities with smaller degree value and greater intermediate centrality had stronger transit ability.