In order to make up the deficiency of the traditional measuring method in monitoring the whole deformation and real-time monitoring of the bridge and overcome the defect of digital photography in monitoring the three-dimensional deformation of a bridge, this paper presented the image matching-time baseline parallax method: a digital camera was set up in the proper place, and a reference plane, consisting of reference points, was not far from the digital camera. Reference plane was perpendicular to the photographic direction, and the monitoring points were on the bridge. The two-dimensional deformation on the object plane of the deformation point was obtained based on image matching-time baseline parallax method, then the horizontal deformation on object plane was disassembled into the bridge direction and the direction perpendicular to bridge direction based on the principle of three-dimensional deformation monitoring, The three-dimensional deformation of the bridge was got. Results showed that measurement accuracy of the bridge was 0.72 mm and 1.16 mm in X and Z direction on object plane, respectively. It could meet accuracy requirements of deformation monitoring. As Phoenix mountain road-bridge showed good flexibility in X, Y, Z and comprehensive direction, and the absolute of the maximum positive and negative deflection was 7.57 mm, which was approximately equal to 1/8 of the allowable deflection of the bridge (L/1 000), and the bridge was in good health. Bridge health monitoring and warning system could achieve the integration of data acquisition, storage, processing and display. The deformation curves could show the deformation trend of the bridge and effectively warn the potential danger.