山东大学学报 (工学版) ›› 2023, Vol. 53 ›› Issue (3): 147-154.doi: 10.6040/j.issn.1672-3961.0.2022.398
• 化学与环境 • 上一篇
朱雨婷1,严文保2,徐菲1,姜政廷3,赵楠4,丁磊1*
ZHU Yuting1, YAN Wenbao2, XU Fei1, JIANG Zhengting3, ZHAO Nan4, DING Lei1*
摘要: 为了解中国一般人群体内全氟及多氟烷基化合物(per- and polyfluoroalkyl substances,PFASs)的暴露水平,通过超高效液相色谱串联质谱法测定济南市84名非职业暴露人群血清样本中19种传统和新型PFASs,并探究不同性别、年龄和身体质量指数(body mass index, BMI)参与者PFASs暴露水平的差异。研究结果表明:大多数种类的PFASs都能检出,其中全氟辛酸、全氟辛基磺酸和全氟己烷磺酸的中值质量浓度较高,分别为14.0、8.4和2.5 ng/mL,6∶2氯代多氟醚基磺酸这一新型PFAS的中值质量浓度也可达1.8 ng/mL,仅次于上述3种传统PFASs;大多数PFASs在血清中的质量浓度水平显著正相关,提示其有相似的来源、暴露途径和/或代谢过程;部分血清PFASs质量浓度在性别、年龄段、BMI组中存在显著差异。本研究为后续PFASs的人群暴露与健康风险研究的先导性研究。
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