关键词: 互信息, 边缘互方差, 医学图像配准

Abstract: Gives a new algorithm of medical image registration based on maximum of mutual information (MMI) and edge correlative deviation. This algorithm combines the edge correlative deviation of the reference image and floating image with the mutual information values of original images, and builds a new function to guide the searching course and thereby to realize the registration. Comparing to the standard MMI, this new algorithm accords with the individuality of images, by avoiding the instability brought by the mutual histogram but considering the information of the voxels' intensity values. Tests have proven that this new method additionally has several improved attributes in aspects of the more obvious climaxes of parameters' curves, more diminished errors on extremes conditions that images lack intensity values, better robust when resisting aggravated white noise.

Key words: edge correlation deviation, medical image registration , : mutual information