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山东大学学报(工学版) ›› 2011, Vol. 41 ›› Issue (2): 102-106.

• 控制科学与工程 • 上一篇    下一篇

重采样对脉搏间期序列谱分析的影响

李丽萍1,杨静2,刘常春1,刘澄玉1,张庆广1,李可1   

  1. 1. 山东大学控制科学与工程学院, 山东 济南 250061; 2. 山东大学计算机科学与工程学院, 山东 济南 250101
  • 收稿日期:2010-11-22 出版日期:2011-04-16 发布日期:2010-11-22
  • 作者简介:李丽萍(1982- ),女,山东青岛人,博士研究生,主要研究方向为生物医学信号处理.Email: liliping@mail.sdu.edu.cn
  • 基金资助:

    国家高技术研究发展计划(863计划)资助项目(2006AA02Z4D9, 2009AA02Z408)

The effect of re-sampling on spectral analysis of pulse interval series

LI Liping1, YANG Jing2, LIU Changchun1, LIU Chengyu1, ZHANG Qingguang1, LI Ke1   

  1. 1. School of Control Science and Engineering, Shandong University, Jinan 250061, China;
    2. School of Computer Science and Technology, Shandong University, Jinan 250101, China
  • Received:2010-11-22 Online:2011-04-16 Published:2010-11-22

摘要:

研究了重采样对脉搏间期序列谱分析的影响,提出以平均脉率为重采样率对脉搏间期序列进行重采样,为脉率变异性分析提供理论支持。采用最近邻点插值、分段线性插值、分段三次Hermite插值和三次样条插值4种方法对仿真脉搏间期序列重采样,并对比相应的Welch周期图法和AR(Autoregressive)自回归模型法的谱分析结果。提出以平均脉率作为重采样率,并与其他多个重采样率进行比较。结果表明,以平均脉率为重采样率,采用三次样条插值方法及Welch周期图法进行谱分析时,所得误差最小,适合用于脉搏间期序列的谱分析。采用该方法对30例健康者和30例冠心病患者的脉搏间期序列进行了谱分析,结果显示冠心病患者的谱分析结果显著低于健康者,验证了本方法的有效性。

关键词: 非均匀采样, 脉搏信号, 重采样, 谱分析, 脉率变异性

Abstract:

The effect of resampling on spectral analysis of pulse interval series was systematically analyzed. The method of the mean pulse rate as the resampling rate was proposed, which could provide theoretical support for  pulse rate variability. Four methods, the nearest neighbor interpolation, piecewise linear interpolation, piecewise cubic Hermite interpolation and cubic spline interpolation, were applied to resample the simulated pulse interval series. The Welch periodogram and the Autoregressive model were used for spectral analysis with several resampling rates compared. Results showed that the combination of cubic spline interpolation and the Welch periodogram to be an optimal choice for least errors and spectral analysis of pulse interval series. And the mean pulse rate was the optimal resampling rate. Thirty healthy subjects and thirty subjects with coronary heart disease (CHD) were tested to verify the effectiveness of the proposed methods. Results showed that spectral analysis of the subjects with CHD was significantly lower than that of the healthy subjects.

Key words: unevenly sampling, pulse signal, re-sampling, spectral analysis, pulse rate variability

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